2020114(火)

White to off-White Powder Enfuvirtide Acetate


White to off-White Powder Enfuvirtide Acetate (T-20) Posted by freemexy on October 7th, 2019Sequence: CH3CO-Tyr-Thr-Ser-Leu-Ile-His-Ser-Leu-Ile-Glu-Glu-Ser-Gln-Asn-Gln-Gln-Glu-L ys-Asn-Glu-Gln-Glu-Leu-Leu-Glu-Leu-Asp-Lys-Trp-Ala-Ser-Leu-Trp-Asn-Trp-Phe- NH2 Cas No.5%max Amino Acid Composition: ±10% of theoretical Peptide Content (N%): ≥80.0~105.0%min. It works by disrupting the HIV-1 molecular machinery at the final stage of fusion with the target cell, preventing uninfected cells from becoming infected.0% Description: Enfuvirtide powder is an antiretroviral drug used in combination therapy for the treatment of HIV-1/AIDS.

0% TrifluoroAcetate Content(HPIC): ≤12. It is marketed under the trade name Fuzeon (Roche). Appearance: White to off-white amorphous solid Single Impurity (HPLC): 0..: 159519-65-0 Molecular Formula: C204H301N51O64 Molecular Weight: 4492 Purity (HPLC): 98.0% MS (ESI): Consistent Mass Balance: 95.0% Water Content (Karl Fischer): ≤8. Applications: Enfuvirtide (INN) Vitamin Series is an HIV fusion inhibitor, the first of a novel class of antiretroviral drugs used in combination therapy for the treatment of HIV-1 infection. It binds to the first heptad-repeat (HR1) in the gp41 subunit of the viral envelope glycoprotein and prevents the conformational changes required for the fusion of viral and cellular membranes







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