Hearing loss is a real problem as people get older. They exposed cells from a mouse cochlea, grown in a lab dish, to molecules that stimulate the Wnt pathway, which makes the cells multiply rapidly."We hope that our work will allow other scientists to pursue studies of supporting cells and hair cells that have not been possible because such limited quantities of hair cells were available," said Will McLean from MIT.

We used small molecules to activate the supporting cells so they become ec motor proliferative and can generate hair cells," said Xiaolei Yin, an instructor at Brigham and Women's Hospital (BWH).Each human is born with about 15,000 hair cells per ear, these cells detect sound waves and translate them into nerve signals that allow us to hear speech, music, and other everyday sounds.Researchers have discovered a combination of drugs that expands the population of progenitor cells or supporting cells in the ear and induces them to become hair cells, that may offer a potential way to treat hearing loss.

Since the treatment involves a simple drug exposure, it will be easier to administer it to humans, with the help of an injection according to the researchers.Researchers have discovered a combination of drugs that expands the population of progenitor cells or supporting cells in the ear.Carrying forward a previous study that found that structural support in the cochlea express provide some of the same surface proteins as intestinal stem cells. It's very much of an unmet need, and this is an entirely new approach," said Robert Langer,a Professor at Massachusetts Institute of Technology (MIT) in US. Once damaged, these cells cannot regrow.The researchers decided to explore whether the same approach would work on supporting cells.

Hearing loss is a real problem as people get older Boston: Scientists have found a cocktail of drugs that can regenerate hair cells in the inner ear, an advance that may pave the way for new treatments against hearing loss.Once they had a large pool of immature progenitor cells, the researchers added another set of molecules that provoked the cells to differentiate into mature hair cells, producing 60 times more mature hair cells than previously used techniques

In cases where there is no underlying medical condition, the condition can be effectively treated with medication, which usually involves a monthly injection that delays further development. We'd never heard about it. This determines that they are not signs of puberty, but just normal variations.Charlene Denton, a British woman whose daughter started puberty at the age of two, told how she discovered the signs of her child's condition.Obesity may also contribute to earlier puberty.This has been noted particularly in young girls.He explained that children can have isolated breast development and pubic hair without other symptoms. In such a situation, the case is referred by the medical experts as 'idiopathic precocious puberty'."

However, the treatment for precocious puberty depends on the cause.But the condition is more difficult to diagnose than often thought.The upper age for diagnosing the condition is undefined, but medical experts generally say it is before the age of eight in boys and nine in girls.jpeg In approximately 90 percent of girls experience precocious puberty.Adding, "We were completely shocked.As per a report in The Independent, precocious puberty is a medical condition that causes an early release of hormones from the pituitary gland and the hypothalamus areas in the brain, which in turn stimulates estrogen production, causing puberty to begin prematurely.In approximately 90 percent of girls experience precocious puberty.In approximately 90 percent of girls and 50 percent of boys who experience precocious puberty, no underlying cause can be identified."Just after her second birthday she started developing little breast buds. At first the doctor reassured us that she was absolutely fine and there was nothing wrong with her.

Pediatrician Paul Kaplowitz said only one in 10 of the children referred to him with signs of early puberty had true precocious puberty. pump motors Suppliers AA Lonely women.The symptoms of precocious puberty include breast development, rapid height growth, menstruation, acne, enlarged testicles or penis, or pubic or underarm hair. But then she started developing a second breast bud, so we took her back and had all sorts of tests done to diagnose her with precocious puberty," she said. The rise in child obesity levels linked to data suggesting the average age of starting puberty in the USA and Europe has gradually become slightly earlier because the more fat cells in the body, the more estrogen storage there is.London, England: While puberty is usually considered to hit an individual during the early teenage, the past couple of months have seen a surge in the cases of precocious puberty, the condition where the body starts to develop when children are as young as even two years old.

When the cause can be identified, it is generally either an abnormality involving the brain or a problem such as a tumor or genetic abnormality in the ovaries, testes or adrenal glands, causing overproduction of sex hormones. The rare condition affects around one in 5,000 to one in 10,000 children five to 10 times more common in girls as compared to boys.The primary goal of treatment is to enable the child to grow to a normal adult height because the condition can stunt their growth.

However, look hard enough and you will find some switchgear shared with Toyota cars and the key fob looks especially low-rent for a car of this price. This NX300h is all-wheel drive, so there is one electric motor powering the front wheels, one powering the rear wheels and one generator that works as an engine starter as well as recharges the battery packs.The driveThis SUV is powered by a 2.There is ample leg and knee room in the back seat but for some taller folks, the rear headroom is very limited.The combined battery and petrol power results in excellent initial responsiveness to throttle inputs.

You can choose between Eco, Normal and Sport modes to alter throttle and gearbox response using a rotary knob on the console.11 lakh) and Luxury (Rs 56. Actually, in a way the NX300h wants you to drive in a sedate manner and that is when you really begin to appreciate its relaxed and silent nature. The engine is extremely silent and devoid of any vibrations or sounds at cruising speeds.The ExteriorIn terms of dimensions, this car is a bit shorter and narrower than a Mercedes-Benz GLC. This SUV, a family luxury car, is both for the city as well as for the weekend getaways, will surely temp you to own it..The soft-touch materials, aluminium panels, the soft synthetic leather seats, all feel truly lovely and the steering wheel is also great to hold.Should I buy one?Although this NX300h might seem a bit pricey, there is a great deal going in it favour. But it will attract potential buyers of Mercedes-Benz GLC, BMW X3, Audi Q5, and the Jaguar F-Pace. I took the Luxury model for a long drive through different terrains to test what it promises. Also, limiting this car’s practicality is the rather tiny boot space due to the raised boot floor, below which sits a full-size alloy spare wheel, which eats up a significant portion of the cargo area.The InteriorThe dashboard, a mixture of different styling elements, is very pleasing to the eyes.However, try speeding this car and it begins to feels sluggish but builds speed without any urgency.Undoubtedly, the Lexus NX300h looks unique and the exterior design is quite simply stunning from certain angles.Interestingly, the NX300h comes with what Lexus calls ‘adaptive variable suspension’ that continuously adjusts damper stiffness based on the conditions.

However, both variants get 18-inch wheels, LED headlights and tail-lights with dynamic turn indicators, a roof spoiler and a large fixed panoramic glass roof.This most affordable Lexus NX300h SUV like the ES300h sedan and the RX450h crossover, is also a hybrid and that will be one of its key USPs (unique selling proposition). Lexus, the Japanese Toyota-owned luxury car brand, which began its operations in India in March 2017, is quietly making its inroads in the highly competitive 40,000 unit plus luxury car market in the country. The oversized spindle-shaped front grill, sharp cuts and creases all along the exteriors and rather unconventional design cues really make it stand out from the crowd.The Lexus NX300h SUV comes in two variants – the F Sport (Rs 59. The steering is very light, and really sharp so it inspires confidence while driving in a spirited manner.5-litre petrol motor churning out 197hp at 5,700rpm and 210Nm of torque at 4,200-4,400rpm.

The black and white theme with contrast stitching looks very tasteful, but what is even better is the quality of materials on the inside and the fit-finish. It has very stylish, sports unique design and high quality interiors and long list of equipment to get your money&ac motors Factory39;s worth really.Lexus has introduced a hybrid crossover called the NX300h which is well-equipped, comfortable, very stylish and an eye catcher everywhere you go.The front grill is a bit different in the F-Sport variant, and the Luxury variant, and also the bumpers.Lexus, the Japanese Toyota-owned luxury car brand, which began its operations in India in March 2017, is quietly making its inroads in the high.  Despite the large 18-inch wheels, the 225mm tyres do well to flatten bad surfaces and this SUV has a nice # and absorbent ride for the most part.71 lakh) models. Lexus has introduced a hybrid crossover called the NX300h which is well-equipped, comfortable, very stylish and an eye catcher everywhere you go

The company last received $100 million from Flipkart&air compressor motors Factory39;s Co-Founder Sachin Bansal. The Korean automotive firm invested $250 million in the Southeast Asian cab-hailing company Grab about four months ago.Bhavish Aggarwal, Co-Founder and CEO of Ola said, the partnership would bring to market a new generation of mobility solutions, as it expands its range of offerings for consumers..This is part of a strategic partnership under which the companies will jointly work toward creating mobility solutions for the global markets. Bhavish Aggarwal, Co-Founder and CEO of Ola said, the partnership would bring to market a new generation of mobility solutions, as it expands its # range of offerings for consumers.

The investment also reflects Ola's efforts to raise money from other investors in an attempt to keep existing investor Japan's SoftBank at bay.This is part of a strategic partnership under which the companies will jointly work toward creating mobility solutions for the global markets."This partnership will also significantly benefit driver-partners on our platform, as we collaborate with Hyundai to build vehicles and solutions that enable sustainable earnings for millions of them, in the time to come," Aggarwal pointed out."India is the centerpiece of Hyundai Motor Group's strategy to gain leadership in the global mobility market and our partnership with Ola will certainly accelerate to transform into a smart mobility solutions provider," Euisun Chung, Executive Vice-Chairman at Hyundai Motor Group, said.Significantly, this investment shows Hyundai's continued interest in the cab-hailing space.

Pune: Hyundai, India's second biggest car maker and Kia Motors (part of Hyundai) on Tuesday said they had invested $300 million or about Rs 2,000 crore in India's ride-hailing giant Ola, marking their biggest combined investment. The agreement will see the three companies extensively collaborate on developing unique fleet and mobility solutions.It would also entail building India-specific electric vehicles and infrastructure as well as nurturing best in class opportunities and offerings for aspiring driver partners with customised vehicles, on the Ola platform

5 per cent and global warming and climate change (12.The study titled "Perception Study on Air Quality" by the ASAR Social Impact Advisors, which works on social and environmental issues, said the awareness level was higher in the metros with the Delhi and National Capital Region (NCR) respondents showing the maximum awareness of all three terms -- Air Quality Index, Particulate Matter 2.The top four causes of the deteriorating air quality were identified to be motor vehicles (74 per cent), industrial units (58 per cent), tree cutting (56.The respondents also believe that the top three environmental issues that affect personal health are air pollution (maximum at 46.

There is a desperate need for a national-level campaign, aimed at addressing belief systems and changing behaviour," he said."This perception needs to be addressed.The study covers cities with a highly-polluted air -- Delhi-NCR, Kolkata, Patna, Lucknow, Varanasi, Amritsar, Singrauli, Dhanbad, Raipur, Korba, Chandrapur, Angul, Nagpur and cities becoming rapidly polluted -- Bengaluru, Pune, Mumbai and Chennai. It is only when people make this a priority issue will the politicians wake up and take action," Debi Goenka, member of the Conservation Action Trust, said.

The top two sources of AQI information for those who were aware and who understood AQI were newspapers and mobile apps, pump motors Manufacturers the study said.About 89 per cent people in Delhi felt sickness or discomfort due to the bad air quality and most of them believed that motor vehicles and felling of trees were the major causes behind pollution, the study said.9 per cent) and construction activities (48.Ashutosh Dikshit, CEO of URJA, the apex body of Delhi's residential welfare associations (RWAs), said, "This exhaustive survey reaffirms the fact that people are aware of air pollution. However, looking at the violations on Diwali night in most parts of north India, I feel that people do not fully believe in the stated causes of air pollution and its proportionate impact. The respondents also believe that the top three environmental issues that affect personal health are air pollution, drinking polluted water and global warming and climate change

About 89 per cent people in Delhi feel sickness or discomfort due to the bad air quality and most of the people believe vehicles and felling of trees are the major causes behind pollution, according to a new study..People who feel the air quality has become "much worse" belong to Angul, Delhi-NCR, Lucknow and Patna and the people of Chennai, Raipur, Mumbai, Korba and Pune feel it has become a "little worse", according to the study.5 and Particulate Matter 10.As many as 5,000 people were interviewed across different demographics in 17 cities for the study.4 per cent), drinking polluted water (19.The survey also showed that the age group which "always" sought AQ information was 18-25 years.A majority of the respondents (33.

They also do not correlate air pollution as a significant contributor to their existing or future health condition.2 per cent).A majority of the respondents (33.4 per cent) said they accessed air quality information "sometimes" and 12 per cent said "never".4 per cent) said they accessed air quality information "sometimes" and 12 per cent said "never".2 per cent)