2020714(火)

They just went ahead and did it

The baby’s birth occurred on April 6, and was reported by New Scientist on September 27..These data are from what is either a long abstract or a very skimpy article in Fertility and Sterility, available online and due to be published on October 19. First, let us hope the child is and remains as healthy as the announcement says he is.Of course, it wasn’t straightforward.News broke this week that the first “three-parent” baby had been born. Indeed, a little of the prospective mother’s mtDNA may, by mistake, be moved too. Rather, he created one, in an unprecedented way.What if we come to a consensus about what should not be allowed and then some renegade scientists, convinced that they know best, just go ahead and do it The future of humanity just took on a new and worrying aspect. That date coincides with the annual meet of the American Society for Reproductive Medicine, at which we may learn more. A technological solution is to find a way of using someone else’s mtDNA. Zhang had, in 2003, made a similar effort in China but authorities there banned the process after his failure: The twins died in premature childbirth.

While the mother’s mtDNA is only a tiny fraction of her total DNA, the 37 genes involved are vital to cellular function, and are always inherited from the mother. The approach Zhang took is very similar to cloning: The nucleus of a donated egg was removed, and replaced by the nucleus of an egg from the intended mother. Dietrich Egli, a cloning expert, has said that in this case, statistics show the technique “was not carried out well”.He seems healthy now, we hear, but that surprises experts. (That would be unsurprising for cloning, which has very low success rates.

Meanwhile, gene-editing technology is advancing rapidly, and many, but not all, governments are involved in creating new rules for applications that do not yet exist. The fertility doctor created five blastocysts, but only one was viable.92%) but seems healthy. But the untested and controversial nature of the procedure that created the child, and the end run around public policy that it entailed, raise many more questions than answers. “Designer babies”, for short. The FDA itself considered the safety of the procedure in 2014 and decided then that “there is not enough data either in animals or in vitro to move on to humans”.60 ± 0.S. It may not be technically illegal in the U. Nature News quoted one scientist as saying: “They just went ahead and did it. oversight. The number of issues that are still unresolved — it’s just staggering. unless public funds are involved, but Congress has blocked the Food and Drug Administration from authorizing clinical trials. The pregnancy was uneventful; the baby was born at 37 weeks, a little early but within normal range.”The baby exists, and deserves privacy.The UK did recently approve a similar procedure to Zhang’s; as far as is known, he never applied for a license there. Pete Shanks Super ELF G2外部リンク is a regular contributor to Biopolitical Times, the blog of the Center for Genetics and Society. Note that it is not the mtDNA that is transferred, as many assume.What we now know for certain is that national regulations without international cooperation may be almost useless in today’s interconnected world. As David King from Human Genetics Alert has noted.

“It is outrageous that (Zhang and team) simply ignored regulators and went to Mexico, because they think they know better”. In the present case, the parents had difficulty conceiving a healthy baby because about a quarter of the mother’s mitochondrial DNA (mtDNA) has a harmful mutation. Developmental biologist Stuart Newman noted: “Recombining portions of the damaged egg cells of two different women has not been encountered in the evolutionary history of our species. This was then fertilised by injection of sperm, and developed into a blastocyst, the precursor to an embryo, that was ultimately moved into the mother’s womb. But for reasons both of his own health and of science, it is vital that he be monitored closely, and permanently. This happened in Mexico because, said Zhang, there are “no rules” there. There is speculation, for instance, that different kinds of mtDNA may replicate at different rates, so the 2 per cent he has that could cause disease might rise to a worrying proportion.

There are, however, reasons to be concerned. There is a real chance he could eventually develop life-threatening conditions. But Zhang insists that “to save lives is the ethical thing to do”, but his intervention did not save a life.) One did not develop at all and three had chromosomal or genetic abnormalities.” He also suggests subsequent development may produce abnormalities — the process is complicated and outcome, uncertain.Combining reproductive tourism with high-risk experimental science, a New York-based American doctor, John Zhang, took a Jordanian couple, who wish to remain anonymous, to Mexico, in order to avoid U. Among the most worrying possibilities are the creation of children with genetic modifications that could change forever what it means to be human. He does have a little of his mother’s mtDNA (less than 1. Rather, the donor mtDNA stays in the enucleated donor egg and the entire nucleus is transferred.



2020629(月)

This marks the 8th successive year of growth

Audi became the first luxury car manufacturer to open a showroom in North-East India with Audi Guwahati. We proved it by launching the all-new Audi TT Coupe, the new Audi A6 Matrix, the first Avant body style sportscar- the Audi RS 6 Avant and the all-new Audi Q7. We are very confident that we will continue our growth path in 2016 and beyond," King added."Unique initiatives like the Audi Mobile Terminal brought the showroom right to the customer's doorstep, especially in tier II and tier III cities, where we received a huge and a positive response from the customers who are significantly contributing to the transformation of the luxury landscape in India. This marks the 8th successive year of growth for the company and proves the company's consistent performance since its inception in India.The Audi model range in India includes the Audi A3 Sedan, Audi A3 Cabriolet, Audi A4, Audi A6, Audi A7 Sportback, Audi A8 L, Audi Q3, Audi Q5, all-new Audi Q7, Audi TT Coupe, Audi S4, Audi S5 Sportback, Audi S6, Audi RS 5 Coupe, Audi RS 6 Avant, Audi RS 7 Sportback, Audi R8, Audi R8 Spyder, Audi R8 V10 plus and Audi R8 LMX available across the country."We are committed towards bringing new products which are technologically advanced, smart, agile and comfortable.2015 has been an exciting year for Audi. This coupled with a robust dealer footprint, wide product range and on top of it a very motivated and committed team ensured that our growth is sustainable and we are here for the long run," Joe added. (Photo: Pixabay) Audi became the first luxury car manufacturer to open a showroom in North-East India with Audi Guwahati. Apart from further strengthening the fundamentals of a strong and vibrant brand, close customer connect and improved profitability, Audi launched 10 exciting products in India this year each with an innovative positioning and strategy. The year 2015 has seen another year of growth for us and we remained focused towards our aim to provide the best luxury car buying experience to our customers" said Joe King, Head, Audi India.33rd Day Of Lockdown Total Cases 26,283 SHRP Weft Feeder外部リンク.

Audi became the first luxury car manufacturer to open a showroom in North-East India with Audi Guwahati.. Mumbai: Audi, the German luxury car manufacturer, continued its growth momentum with an impressive 11,192 deliveries to the customers in 2015."Audi has been the preferred choice of luxury mobility for car enthusiasts in India. With our perfect pricing and the class defining products packed with the most innovative features, we have been able to offer the best package to our customers.Audi also inaugurated Audi Bengaluru Central, Audi Ranchi, Audi Madurai and Audi Rajkot.



2020624(水)

The country premier policy maker feels that mere changes

Niti Aayog feels that there is a need to examine the entire value chain associated with the industry -- from raw materials to production of finished products -- to discover the bottlenecks in the sector.Last month, the government&air jet loom外部リンク39;s think tank Niti Aayog had floated a working paper where it had mooted a new and dynamic steel policy to bring the over USD 100 billion industry back on track as well as meet the target of 300 million tonnes (MT) capacity by 2025. Sai said the global glut and surge in import prices of steel have adversely affected the domestic steel industry."The Government proposes to revisit the existing National Steel Policy.

The government has proposed to revisit the existing National Steel Policy, the work on which is at "conceptual stage", Parliament was informed on amid the sector reeling under global glut and surge in import prices.Listing the steps taken by the government to support the domestic steel industry, Sai said the ministry has notified the Steel and Steel Products (Quality Control) Orders to check the quality of steel being imported into the country.Also to provide a level playing field to domestic steel producers, government has imposed Minimum Import Price (MIP) on 66 steel products and has also come out with anti-dumping duties on various grades, Sai said.

The country premier policy maker feels that mere changes in the National Steel Policy, 2012, will not help the sector that in the last few years has been flooded with cheap imports from China, Korea and Japan impacting its sales and profits, which has negatively influenced its capacity to repay debts."It has resulted in erosion of # profits of domestic steel companies and has resulted in Non-Performing Assets (NPAs) of domestic steel companies," the minister added.Besides, government has notified the MMDR, Amendment Act, 2015 to streamline grant of mining leases in order to maintain sufficient availability of raw materials for various sectors including steel sector, he said. It is at conceptual stage," Minister of State for Steel Vishnu Deo Sai said in a written reply to Lok Sabha.Another pertinent issue that needs to be ensured that none of these make windfall gains at the expense of others, it added.



2020616(火)

When the boat started to capsize, he said he jumped

He saw a friend in the water, clinging to a plastic bottle.He estimated he saw about 150 people in the "fridge," but his account could not be independently confirmed. He was rescued by fishermen. (Photo: AP) Women broke into screams and some men collapsed whenever they recognized someone, some only by their clothes.The boat was overcrowded with hundreds of people, but the exact number is not known, with estimates from officials ranging from 400 to 600. Some couldn't even hold the rope. "I am not coast guard, I'm a fisherman. They announced that no more bodies were found in the hold, angering relatives of those who still had not been found, many of whom were convinced from earlier reports that more dead were in the hold.

When the boat started to capsize, he said he jumped into the water and swam away from the vessel. But one of his friends pulled him out, meaning he could jump to safety when it began to sink."Only his clothes showed that it's him," she said.He said this was his second attempt to make it to Europe and vowed to try again, citing poverty in Egypt. We need an operation room here to rescue people. Nine of his friends died, he said. There was not an empty centimeter," he said, speaking on condition of anonymity for fear of harassment by police.At the pier, emergency officials wore white medical masks against the smell of the bodies. She spoke on condition of anonymity because she feared harassment by police. I kept swimming, searching for land but couldn't find it," he said.Another survivor, Aboud, said he was originally put in the "fridge" when he was brought on the boat. Rosetta: Rescue workers on Tuesday pulled dozens of bodies from the hold of an Egyptian fishing boat that sank in the Mediterranean Sea carrying hundreds of migrants trying to make it to Europe, bringing the toll from the disaster to more than 200 dead. After his rescue by fishermen, he was taken to the police station where he said he was beaten.Samir Qlamosh, a local water jet loom外部リンク fisherman, has become a hero in Rosetta, touted in social media after he rescued 96 survivors in his boat.Women broke into screams and some men collapsed whenever they recognized someone, some only by their clothes.For days, authorities and fishermen have been recovering bodies from the water or finding them washed up to the shore, ever since the boat capsized and sank before dawn on Sept."

Hassan said his cousin's body was found by fishermen. Egyptian authorities have so far in 2016 foiled 110 attempts to smuggle migrants to Europe. 21 about 12 kilometers (7."I will go once, twice, three times."From 4:00 am to 9:30 am, it was foggy and dark.A woman whose two sons were on the boat found one of them, 18-year-old Ahmed, among the bodies brought to the pier. Once there, he found survivors in the water and fished them out with ropes, he said.As the dead were brought to a pier outside the coastal city of Rosetta, families of the missing went through the grisly task of searching through the body bags for their loved ones.Around 160 of those on board survived, many of them spending hours in the water until rescued by local fishing boats. He spoke on condition he be identified only by his first name for fear of harassment by police. "Here they deal with us like animals. He said that the morning after the sinking, he was returning to the pier and was told by officials to go out and search. But survivors and family members all said the rescues were carried out by local fishermen, further stoking anger that authorities were not doing enough. Some were dying," he told the AP.

"The military said in a statement that it had rescued more than 160 survivors.Authorities pulled 33 dead out of the hold, bringing the toll to 203, the head of a local municipal council, Ali Abdel-Sattar, told The Associated Press.One survivor, a 17-year-old, from the nearby village of al-Gazira al-Khudra, said he and several of his friends were brought out on a smuggler boat with about 150 people and transfered onto the Procession of the Prophet, which he said was already swelling with about 300 people. Where is the coast guard " he said.He searched for 90 minutes until finally officials sent him the coordinates of the site. I looked and only saw the bottle," he said. This year, more than 12,000 migrants arrived in Italy from Egypt between January and September, compared to 7,000 in the same period last year, according to the EU border agency Frontex. We are dead anyway," he said. There, animals have rights.5 miles) off the Egyptian coast.On Tuesday, a crane vessel hauled the boat, called the Mawkib al-Rasoul, or "Procession of the Prophet," out of the mud of the seafloor so that authorities could retrieve dead trapped in the hold, including a cramped section known as the "fridge," where fishermen normally keep their catch on ice.

The sea route from Egypt to Europe has become increasingly popular for migrants. He said the screams from the boat still rang in his ears. Women broke into screams and some men collapsed whenever they recognized someone, some only by their clothes because of the bodies' condition after nearly a week in the water. "Suddenly he disappeared."We got there after people were already worn out."It was full from top to bottom. Most were believed to be Egyptians, many of them young men from poor villages in the Nile Delta, with some others from Sudan or other African countries, and at least one Syrian woman whose body was found washed ashore. But her other son was still missing. She said he no longer had a face after the days in the water. Families of those still missing have been camped out all week at the piers, waiting for word on their loved ones and angrily accusing authorities of not doing enough to find them. "From across Egypt, they can leave in boats.



2020610(水)

In fact, a celebrity cosmetologist admits that most

Malaika Arora Khan, Bipasha Basu and Gauri Khan apparently owe much of their now fair and lovely skin to these makeovers. The actress hasn’t shied away from admitting to her nasal reconstruction, if you will. While most unsuspecting actresses have come under the scanner for their respective enhancements, these two have never let out signals of a possible surgeon’s involvement, so if someone were to get the ‘best job’ trophy, it would undoubtedly be this pretty duo.

Now, juxtaposing a few before/after pictures of PC can help one gauge the journey of her facial features.Malaika Arora KhanAnushka SharmaBut going under the proverbial knife however, is passé. A star sister-couple known for their radiant skin have apparently done much to enhance their cheeks and chin.  But coming back to facial features, some celebs seem to have taken the poem ‘chubby cheeks, dimple chin’ too seriously too. From a chiselled nose to high cheekbones, there’s much that Priyanka owes to her late father, who also happened to be a cosmetic surgeon.The actress hasn’t shied away from admitting to her nasal reconstruction, if you will. I have by no means gone ‘under the knife’ or done any kind of ‘plastic surgery’ or undergone any intrusive procedure,” she had said.A still from Baazigar movieSpeaking of tight lips, Anushka Sharma is one more person who didn’t remain so when the grapevine was abuzz about her lip job gone wrong.

In fact, a celebrity cosmetologist admits that most of his clients categorically ask him to ‘not give them the permanent surprise eyebrows’, now the patent of a certain star wife. But an evergreen favourite remains the botox and the subsequent eyebrow raise — not that everyone who has gotten it done has got desired results. She, like many others however, has remained tight-lipped on the subject.  KajolAnd oh, it doesn’t stop there. The actress however insisted that it was ‘lip enhancing tools and makeup techniques’ that had caused the buzz around her look. While Priyanka may understandably not want to delve into the details of her makeover, others such as Shilpa Shetty for instance, have been more forthcoming. But there’s another reason stars head to Dubai — we’re referring to Sooraj Pancholi, Salman Khan and Ranbir Kapoor in particular. And from what we hear, the procedure may cost upto Rs 40 lakh for a tummy tuck or liposuction. Only these trust Indian doctors in Los Angeles and Dubai far more than those back home. A few star kids also apparently have been known to be in tow. “For a short while now I have been using a temporary lip enhancing tool and that along with make up techniques (I have learnt over the years) is the reason why there might be a change in the appearance of my lips.Priyanka ChopraAnd finally, have you noticed how most stars have an enviable, flashy smile? It’s the veneers! For just for Rs 6 lakh or so, one can look like a toothpaste model.

Not that Bollywood has ever hesitated to spare some change. Shilpa Shetty Priyanka Chopra’s comment on international talk show The View, claiming that she was born with her nose as it looks today, seems to have raised a few eyebrows back home — and no, not in the way it has raised her shapely nose. Reason? Yes, it has much to do with their hair enhancements allegedly. laser weft feeder外部リンク On the other hand, Kajol who unapologetically flashed her unibrow during the peak of her career, seems to have given in to the ways of showbiz and apparently gone for melanin therapy to get a lighter skin tone. And despite the hullabaloo over skin lightening products, it is exactly this procedure that is high in demand now. These three good-looking gentlemen are often spotted in Dubai, often wearing bandanas



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